Clinical Papers
Click Below to download PDF's
Stifle and CCL
Clinical paper references
Smith PA, Bozynski CC, Kuroki K, Henrich SM, Wijdicks CA, Cook JL. Intra-Articular Biocompatibility of Multistranded, Long-Chain Polyethylene Suture Tape in a Canine ACL Model. J Knee Surg. 2019 Jun;32(6):525-531. doi: 10.1055/s-0038-1655765. Epub 2018 May 31. PMID: 29852514.
Gastocnemius/Achilles
Cryotherapy
Clinical paper references
- Wright, B., Kronen, P.W., Lascelles, D., Monteiro, B., Murrell, J.C., Robertson, S., Steagall, P.V.M. and Yamashita, K. (2020), Ice therapy: cool, current and complicated. J Small Anim Pract, 61: 267-271.McCarthy RD, Ordóñez HJ, Semevolos SA.
- In vivo effects of cold therapy and bandaging on core temperatures of equine superficial and deep digital flexor tendons. Vet Surg. 2025 Apr;54(3):470-477. doi: 10.1111/vsu.14235. Epub 2025 Feb 25. PMID: 39996479.
- WI Baltzer (2020) Rehabilitation of companion animals following orthopaedic surgery, New Zealand Veterinary Journal, 68:3, 157-167, DOI: 10.1080/00480169.2020.1722271
- Janas K, Millis D, Levine D, Keck M. Effects of Cryotherapy on Temperature Change in Caudal Thigh Muscles of Dogs. Vet Comp Orthop Traumatol. 2021 Jul;34(4):241-247. doi: 10.1055/s-0041-1723786. Epub 2021 Feb 25. PMID: 33634436.
- Szabo SD, Levine D, Marcellin-Little DJ, Sidaway BK, Hofmeister E, Urtuzuastegui E. Cryotherapy Improves Limb Use But Delays Normothermia Early After Stifle Joint Surgery in Dogs. Front Vet Sci. 2020 Jul 3;7:381. doi: 1c0.3389/fvets.2020.00381. PMID: 32719817; PMCID: PMC7350525.
- Luethy D. Cryotherapy Techniques: Best Protocols to Support the Foot in Health and Disease. Vet Clin North Am Equine Pract. 2021 Dec;37(3):685-693. doi: 10.1016/j.cveq.2021.07.005. PMID: 34782099.
- Quam V, Yardley J, Quam M, Paz C, Belknap J. Cryotherapy provides transient analgesia in an induced lameness model in horses. Can Vet J. 2021 Aug;62(8):834-838. PMID: 34341594; PMCID: PMC8281941.
- Morgan J, Stefanovski D, Lenfest M, Chatterjee S, Orsini J. Novel dry cryotherapy system for cooling the equine digit. Vet Rec Open. 2018 Jan 7;5(1):e000244. doi: 10.1136/vetreco-2017-000244. PMID: 29344364; PMCID: PMC5761284.
- Van Eps AW. Therapeutic hypothermia (cryotherapy) to prevent and treat acute laminitis. Vet Clin North Am Equine Pract. 2010 Apr;26(1):125-33. doi: 10.1016/j.cveq.2010.01.002. PMID: 20381741.
- Orsini JA. The Big Picture in Better Understanding the Equine Foot. Vet Clin North Am Equine Pract. 2021 Dec;37(3):521-528. doi: 10.1016/j.cveq.2021.07.001. Epub 2021 Oct 19. PMID: 34674909.
- , , . Efficacy of a commercial dry sleeve cryotherapy system for cooling the equine metacarpus. Veterinary Surgery. 2022; 51(7): 1070–1077. doi:10.1111/vsu.13847
- Lavado RA, Lewis J, Montgomery JB. Continuous digital hypothermia for prevention and treatment of equine acute laminitis: A practical review. Vet J. 2023 Jul 26;300-302:106016. doi: 10.1016/j.tvjl.2023.106016. Epub ahead of print. PMID: 37507002
- Su EP, Perna M, Boettner F, Mayman DJ, Gerlinger T, Barsoum W, Randolph J, Lee G. A prospective, multi-center, randomised trial to evaluate the efficacy of a cryopneumatic device on total knee arthroplasty recovery. The Journal of Bone and Joint Surgery. 2012; 94-B, Supple A:153-6. https://www.ncbi.nlm.nih.gov/pubmed/23118406.
- Waterman B, Walker JJ, Swains C, Shortt M, Todd MS, Machen SM, Owens BD. The efficacy of combined cryotherapy compression compared with cryotherapy alone following anterior cruciate ligament reconstruction. The Journal of Knee Surgery. 2012; 25, (02):155-160. https://www.ncbi.nlm.nih.gov/pubmed/22928433.
- Murgier J, Cassard X. Cryotherapy with dynamic intermittent compression for analgesia after anterior cruciate ligament reconstruction. Preliminary study. Orthopaedics & Traumatology: Surgery & Research. 2014; 100:309-312. https://www.ncbi.nlm.nih.gov/pubmed/24679367.
- Nabıyev VN, Ayhan S, Adhıkarı P, Cetın E, Palaoglu S, Acaroglu RE. Cryo-compression therapy after elective spinal surgery for pain management: a cross-sectional study with historical control. Neurospine. 2018; 15(4):348-352. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347345/pdf/ns-1836070-035.pdf.
- Bellon M, Michelet D, Carrara N, Vacher T, Gafsou B, Ilhareborde B, Mazda K, Ferrero E, Simon AL, Julien‑Marsollier F, Dahmani S. Efficacy of the Game Ready* cooling device on postoperative analgesia after scoliosis surgery in children. European Spine Journal. 2019; 28:1257–1264. https://link.springer.com/article/10.1007%2Fs00586-019-05886
- Klaber I, Greeff E, O’Donnell J. Compressive cryotherapy is superior to cryotherapy alone in reducing pain after hip arthroscopy. Journal of Hip Preservation Surgery. 2019; 0(0):1-6. https://academic.oup.com/jhps/advance-article/doi/10.1093/jhps/hnz048/5610188.
- Murgier J, Cailliez J, Wargny M, Chiron P, Cavaignac E, Laffosse JM. Cryotherapy with dynamic intermittent compression improves recovery from revision total knee arthroplasty. The Journal of Arthroplasty. 2017; 1-4. https://pubmed.ncbi.nlm.nih.gov/28465126.
- Leegwater NC, Willems JH, Brohet R, Nolte PA. Cryocompression therapy after elective arthroplasty of the hip. Hip International. 2012; 22 (05):527-533. https://www.ncbi.nlm.nih.gov/pubmed/23112075
APAVAC Immunotherapy
Clinical paper references
Frayssinet,
Patrick & Mathon, Didier & Simonet, Michel & Trouillet, Jean &
Valerie, Mathon & Rouquet, Nicole. (2020). TREATMENT OF CANINE OSTEOSARCOMA
USING AUTOLOGOUS ACTIVE IMMUNOTHERAPY WITH OR WITHOUT SURGERY.
10.22533/at.ed.54620071223.
Marconato L, Stefanello D, Sabattini S, Comazzi
S, Riondato F, Laganga P, Frayssinet P, Pizzoni S, Rouquet N, Aresu L. Enhanced
therapeutic effect of APAVAC immunotherapy in combination with dose-intense
chemotherapy in dogs with advanced indolent B-cell lymphoma. Vaccine. 2015 Sep
22;33(39):5080-6. doi: 10.1016/j.vaccine.2015.08.017. Epub 2015 Aug 18. PMID: 26296495.
Dias JNR, André AS, Aguiar SI, Gil S, Tavares
L, Aires-da-Silva F. Immunotherapeutic Strategies for Canine Lymphoma: Changing
the Odds Against Non-Hodgkin Lymphoma. Front Vet Sci. 2021 Aug 26;8:621758.
doi: 10.3389/fvets.2021.621758. PMID: 34513964; PMCID: PMC8427286.
Marconato L, Aresu L, Stefanello D, Comazzi S,
Martini V, Ferrari R, Riondato F, Rouquet N, Frayssinet P, Sabattini S.
Opportunities and challenges of active immunotherapy in dogs with B-cell
lymphoma: a 5-year experience in two veterinary oncology centers. J Immunother
Cancer. 2019 Jun 7;7(1):146. doi: 10.1186/s40425-019-0624-y. PMID: 31174615;
PMCID: PMC6554898.
Simonet M, Rouquet N and Frayssinet P (2013) Hydroxylapatite
(HA) Powder for Autovaccination Against Canine Non Hodgkin’s Lymphoma. Advances
in Biomaterials Science and Biomedical Applications. InTech. DOI:
10.5772/55129.
Marconato L, Frayssinet P, Rouquet N, Comazzi
S, Leone VF, Laganga P, Rossi F, Vignoli M, Pezzoli L, Aresu L. Randomized,
placebo-controlled, double-blinded chemoimmunotherapy clinical trial in a pet
dog model of diffuse large B-cell lymphoma. Clin Cancer Res. 2014 Feb
1;20(3):668-77. doi: 10.1158/1078-0432.CCR-13-2283. Epub 2013 Dec 3. PMID:
24300788.
Thiéry E, Marano I, Cadiergues MC, Semin MO, Sayag D, Raymond I, Lallemand E, Prise en charge multimodale d’un carcinome épidermoïde multicentrique incluant l’immunothérapie, Pratique Vétérinaire Equine, mars 2022, N°0213.
Simonet P, Mastocytomes canins et immunothérapie autologue, Cas cliniques, Vetofocus, 12/ 2017
Get in Touch
Find out more about how your patients or pet can benefit from Vetlig products: